Tore Nielsen
Dedicated to dream research in all its aspects. I run a sleep lab for cognitive testing (including a VR room) and biorecording (EEG, EMG, ECG, HR, respiration, etc.). Nightmares and sleep onset imagery are current areas of focus.
I have a side interest in the effects of intermittent fasting and caloric restriction on health and longevity.
I write. I write. I write. I write!
Address: Dream & Nightmare Laboratory
Center for Advanced Research in Sleep Medicine,
Hopital du Sacre-Coeur de Montreal,
5400 boul. Gouin Ouest
Montreal, Quebec, Canada H4J 1C5
I have a side interest in the effects of intermittent fasting and caloric restriction on health and longevity.
I write. I write. I write. I write!
Address: Dream & Nightmare Laboratory
Center for Advanced Research in Sleep Medicine,
Hopital du Sacre-Coeur de Montreal,
5400 boul. Gouin Ouest
Montreal, Quebec, Canada H4J 1C5
less
InterestsView All (20)
Uploads
Peer-reviewed research papers by Tore Nielsen
Methods: Adults with CCHD, resting arterial oxygen saturation b90%, and systemic ejection fraction N40% were prospectively enrolled in a cross-sectional study. To assess sleep and respiratory indices, subjects underwent a standardized clinical appraisal that included arterial blood gas analysis and a comprehensive sleep study with an ambulatory device. An apnea–hypopnea index (AHI) ≥5/h was considered to indicate sleep apnea.
Results: Ten adults with CCHD, aged 38±11 years, completed the study. Seven patients had elevated pulmonary artery pressures, with a mean systolic pressure of 86.3±18.1 mm Hg. All patients demonstrated normal sleep parameters. Oxygen saturation further declined in 5 patients during sleep. However, no associated alteration in respiratory parameters was observed and no significant arrhythmia. The mean AHI was 1.1±1.0/h. No subject met the pre-defined criterion for sleep apnea.
Conclusion: Although further oxygen desaturation may be observed during sleep in patients with CCHD, it occurs in the absence of sleep disordered breathing.
Design: The associational breadth task was applied in both a priming condition, where cue words were signaled to be memorized prior to sleep (primed), and a nonpriming condition, where cue words were not memorized (nonprimed). Cue words were either emotional (positive, negative) or nonemotional. Participants were randomly assigned to either an awake (WAKE) or a sleep condition, which was subsequently split into NREM or REM groups depending on stage at awakening.
Setting: Hospital-based sleep laboratory.
Participants: Fifty-eight healthy participants (22 male) ages 18 to 35 y (mean age = 23.3 ± 4.08 y).
Measurements and Results: The REM group scored higher than the NREM or WAKE groups on primed, but not nonprimed emotional cue words; the effect was stronger for positive than for negative cue words. However, REM time and percent correlated negatively with degree of emotional priming. Priming occurred for REM awakenings but not for NREM awakenings, even when the latter sleep episodes contained some REM sleep.
Conclusions: Associational breadth may be selectively consolidated during REM sleep for stimuli that have been tagged as important for future memory retrieval. That priming decreased with REM time and was higher only for REM sleep awakenings is consistent with two explanatory REM sleep processes: REM sleep consolidation serving emotional downregulation and REM sleep inertia.